Connectivity Map

Connectivity Map. Interns Tutor/Mentor Connection Interns Map Growth of Network These results indicate the feasibility of the approach and suggest the value of a large-scale community Connectivity Map project. The data is used to find the functional connections between drugs, genes, and diseases through the transitory feature of common gene-expression changes.

Connectivity map displaying the predicted functional associations
Connectivity map displaying the predicted functional associations from www.researchgate.net

The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework Lamb et al.' (1) is biased in favor of establishing the usefulness of a connectivity map for revealing connections among small molecules, genes, and diseases by generating gene-expression.

Connectivity map displaying the predicted functional associations

We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs, and disease states are connected by virtue of common gene-expression signatures These results indicate the feasibility of the approach and suggest the value of a large-scale community Connectivity Map project. 摘要:Connectivity Map 是药物基因组学研究领域的重要数据库,是 计算生物学 和药物筛选研究人员做研究时不得不重视的数据库。 它不仅提供大量宝贵的药物处理人类细胞系前后的基因表达谱数据,而且也提供了基于 模式匹配算法 的在线工具,用户提交合适的基因列表就能得到该数据库中与之相关.

Data Center Network Map TulsaConnect. We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs, and disease states are connected by virtue of common gene-expression signatures We demonstrate that this "Connectivity Map" resource can be used to find connections among small molecules sharing a mechanism of action, chemicals and physiological processes, and diseases and drugs

Connectivity Map (CMap) analysis in MDAMB468 cells exposed to. The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them 摘要:Connectivity Map 是药物基因组学研究领域的重要数据库,是 计算生物学 和药物筛选研究人员做研究时不得不重视的数据库。 它不仅提供大量宝贵的药物处理人类细胞系前后的基因表达谱数据,而且也提供了基于 模式匹配算法 的在线工具,用户提交合适的基因列表就能得到该数据库中与之相关.